BDBM50397728 CHEMBL2181976
SMILES Cc1cc(C)cc(c1)-c1nc(NC(=O)c2cccnc2)sc1-c1ccncc1
InChI Key InChIKey=YDXZLBYHXZOWOC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50397728
Affinity DataKi: 0.360nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]I-AB-MECA from human rat adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Displacement of [125I]I-AB-MECA from rat adenosine A3 receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 9.60nMAssay Description:Displacement of [125I]I-AB-MECA from mouse adenosine A3 receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 121nMAssay Description:Displacement of [3H] ZM241385 from human adenosine A2A receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 162nMAssay Description:Displacement of [3H] DPCPX from human adenosine A1 receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 163nMAssay Description:Displacement of [3H] DPCPX from rat adenosine A2B receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 189nMAssay Description:Displacement of [3H] DPCPX from mouse adenosine A2B receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of [3H] DPCPX from human adenosine A2B receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 333nMAssay Description:Displacement of [3H] DPCPX from rat adenosine A1 receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 411nMAssay Description:Displacement of [3H] DPCPX from mouse adenosine A1 receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: >666nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 790nMAssay Description:Binding affinity to human 5-HT2C receptor by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: >826nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 830nMAssay Description:Displacement of [3H] ZM241385 from mouse adenosine A2A receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 960nMAssay Description:Binding affinity to human 5-HT2A receptor by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.15E+3nMAssay Description:Displacement of [3H] ZM241385 from rat adenosine A2A receptor expressed in HEK293 cells incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 3.70E+3nMAssay Description:Binding affinity to human M5 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.550nMAssay Description:Binding affinity to human adenosine A3 receptor expressed in HEK293 cells measured by radioligand binding assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKd: 3.70nMAssay Description:Binding affinity to mouse adenosine A3 receptor expressed in HEK293 cells measured by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.80nMAssay Description:Binding affinity to rat adenosine A3 receptor expressed in HEK293 cells measured by radioligand binding assayMore data for this Ligand-Target Pair